You can solo using a frigate, but it requires 3x filament and has more loot than doing 1x filament with a cruiser.
In the first room you are invulnerable for 1 minute and in the other rooms 15 seconds. The enemies will not attack until then. Use that time to examine the pylons, clouds, caches, and enemies.
Gates will not open until all enemies are dead.
Extraction nodes are optional. Sometimes they have no loot.
Biocombinative Cache always has loot and is the most important container.
A Mobile Tractor Unit (MTU) can be used to pull the extraction node loot for you.
If you go out of bounds you will die. An orange barrier appears if you get close.
Use “C” shortcut to Track objects and look at them to find them easier.